English Reference Manual Pipette Calibration Module MCP-R
Deutsch Referenzhandbuch Pipettenkalibriermodul MCP-R
Español Manual de referencia Módulo de calibración de pipetas MCP-R
Français Manuel de référence Module d’étalonnage de pipettes MCP-R
简体中文 參考手冊 移液器校准模块 MCP-R
日本語 リファレンスマニュアル ピペット校正モジュール MCP-R
30491872A2022/10/05 13:13- Schema ST4 PDF engine -Layout by Victor Mahler
Table of Contents
1 Introduction 3
1.1 Document purpose.......................................................................................... 3
1.2 Further documents and information................................................................... 3
1.3 Explanation of conventions and symbols used ................................................... 3
1.4 Acronyms and abbreviations ............................................................................ 3
1.5 Product compatibility....................................................................................... 4
2 Safety Information 4
2.1 Definitions of signal words and warning symbols ............................................... 4
2.2 Product-specific safety notes ............................................................................ 4
3 Function 5
3.1 Function description ........................................................................................ 5
4 Installation 5
4.1 Selecting the location....................................................................................... 6
4.2 Scope of delivery............................................................................................. 7
4.2.1 MCP-R pipette calibration module...................................................... 7
4.2.2 Documentation................................................................................ 7
4.3 Installing the MCP-R pipette calibration module on the balance ............................ 8
5 Operation 8
5.1 Filling the evaporation trap............................................................................... 8
5.2 Performing a pipette calibration ........................................................................ 8
5.3 Performing a test............................................................................................. 9
5.3.1 Performance test or sensitivity test ..................................................... 9
5.3.2 Positioning test................................................................................ 10
5.3.3 MCP repeatability test....................................................................... 11
6 Maintenance 11
6.1 Maintenance tasks .......................................................................................... 12
6.2 Emptying the containers................................................................................... 12
6.2.1 Emptying the containers manually ..................................................... 12
6.2.1.1 Emptying the pipetting tanks ........................................................ 12
6.2.1.2 Emptying the evaporation trap...................................................... 12
6.2.2 Emptying the containers with the pump .............................................. 13
6.2.2.1 Assembling the pump ................................................................. 13
6.2.2.2 Emptying the pipetting tanks ........................................................ 13
6.2.2.3 Emptying the evaporation trap...................................................... 13
6.3 Disassembling for cleaning.............................................................................. 14
6.4 Cleaning ........................................................................................................ 15
6.4.1 Cleaning the instrument.................................................................... 16
6.4.2 Cleaning after an overflow ................................................................ 16
6.5 Putting into operation after cleaning .................................................................. 16
6.6 Adjusting the holder for pipetting tanks .............................................................. 17
6.6.1 Horizontal adjustment ...................................................................... 17
6.6.2 Vertical adjustment .......................................................................... 17
7 Troubleshooting 17
7.1 Error symptoms .............................................................................................. 18
8 Technical Data 18
8.1 General data................................................................................................... 18
8.2 Dimensions.................................................................................................... 19
1Pipette Calibration Module
en
9 Accessories and Spare Parts 20
9.1 Accessories.................................................................................................... 20
9.2 Spare parts..................................................................................................... 21
10 Disposal 21
11 Compliance Information 22
2 Pipette Calibration Module
1 Introduction
Thank you for choosing a METTLER TOLEDO instrument. The instrument combines high performance with ease
of use.
1.1 Document purpose
This manual is intended to support trained staff when using the product described herein.
Restriction of content
This manual does not describe the following items:
The balance connected to the product described herein.
Accessories used with the product described herein. Exceptions might apply.
1.2 Further documents and information
This document is available in other languages online.
www.mt.com/MCP-R-RM
Instructions for cleaning a balance, "8 Steps to a Clean Balance":
www.mt.com/lab-cleaning-guide
Search for software:
www.mt.com/labweighing-software-download
Search for documents:
www.mt.com/library
For further questions, please contact your authorized METTLER TOLEDO dealer or service representative.
www.mt.com/contact
1.3 Explanation of conventions and symbols used
Conventions and symbols
Key and/or button designations and display texts are shown in graphic or bold text, e.g., , Edit.
Note For useful information about the product.
Refers to an external document.
Elements of instructions
In this manual, step-by-step instructions are presented as follows. The action steps are numbered and can
contain prerequisites, intermediate results and results, as shown in the example. Sequences with less than two
steps are not numbered.
Prerequisites that must be fulfilled before the individual steps can be executed.
1 Step 1
Intermediate result
2 Step 2
Result
1.4 Acronyms and abbreviations
Original term Explanation
AC Alternating Current
ASTM American Society for Testing and Materials
DC Direct Current
EMC Electromagnetic Compatibility
OIML Organisation Internationale de Métrologie Légale
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3Pipette Calibration Module
(International Organization of Legal Metrology)
RM Reference Manual
SOP Standard Operating Procedure
1.5 Product compatibility
The MCP-R pipette calibration module is only compatible with the listed balance models.
Balance Models designation
XPR105DUHR
XPR106DUHR
2 Safety Information
A document named "Reference Manual" is available for this instrument.
This Reference Manual contains a full description of the instrument and its use.
Keep the Reference Manual for future reference.
Include the Reference Manual if you transfer the instrument to other parties.
Only use the instrument according to the Reference Manual. If you do not use the instrument according to the
Reference Manual or if it is modified, the safety of the instrument may be impaired and Mettler-Toledo GmbH
assumes no liability.
2.1 Definitions of signal words and warning symbols
Safety notes contain important information on safety issues. Ignoring the safety notes may lead to personal
injury, damage to the instrument, malfunctions and false results. Safety notes are marked with the following
signal words and warning symbols:
Signal words
DANGER A hazardous situation with high risk, resulting in death or severe injury if not avoided.
WARNING A hazardous situation with medium risk, possibly resulting in death or severe injury if
not avoided.
CAUTION A hazardous situation with low risk, resulting in minor or moderate injury if not
avoided.
NOTICE A hazardous situation with low risk, resulting in damage to the instrument, other
material damage, malfunctions and erroneous results, or loss of data.
Warning symbols
General hazard Notice
2.2 Product-specific safety notes
Intended use
This instrument is designed to be used by trained staff. The instrument is intended for volumetric calibration of
pipettes only.
Any other type of use and operation beyond the limits of use stated by Mettler-Toledo GmbH without consent
from Mettler-Toledo GmbH is considered as not intended.
4 Pipette Calibration Module
Responsibilities of the instrument owner
The instrument owner is the person holding the legal title to the instrument and who uses the instrument or
authorizes any person to use it, or the person who is deemed by law to be the operator of the instrument. The
instrument owner is responsible for the safety of all users of the instrument and third parties.
Mettler-Toledo GmbH assumes that the instrument owner trains users to safely use the instrument in their
workplace and deal with potential hazards. Mettler-Toledo GmbH assumes that the instrument owner provides
the necessary protective gear.
Safety notes
WARNING
Death or serious injury due to electric shock
Contact with parts that carry a live current can lead to death or injury.
1 Only use the METTLER TOLEDO power cable and AC/DC adapter designed for your
accessory.
2 Connect the power cable to a grounded power outlet.
3 Keep all electrical cables and connections away from liquids and moisture.
4 Check the cables and the power plug for damage and replace them if damaged.
NOTICE
Damage to the instrument or malfunction due to the use of unsuitable parts
Only use parts from METTLER TOLEDO that are intended to be used with your instrument.
3 Function
3.1 Function description
The MCP-R pipette calibration module can be added to compatible balances to perform volumetric calibration
of single and multichannel pipettes. It can contain 12 pipetting tanks that are placed inside the module. The
MCP-R pipette calibration module has a removable evaporation trap door on top that keeps liquids from evapo-
rating during measurements and reduces influences from the outside.
The balance with the installed MCP-R pipette calibration module is connected to a computer with the specific
Calibry software installed that initiates the calibration process and collects all the data. When a calibration is
initiated, the user opens the evaporation trap door and pipettes the required volume into each tank. The tanks
are weighed successively and the data is collected for the evaluation of the pipettes.
Note
The Calibry software is not part of the delivery and can be purchased optionally, see [Accessories
Page20].
See also
Product compatibility Page4
4 Installation
This instrument must be installed by a METTLER TOLEDO service technician.
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5Pipette Calibration Module
4.1 Selecting the location
The MCP-R pipette calibration module is a sensitive precision instrument. The location of use has a profound
effect on the accuracy of the weighing results.
Requirements of the location
Place indoors on stable
table
Ensure sufficient spacing Level the instrument Provide adequate lighting
Avoid direct sunlight Avoid vibrations Avoid strong drafts Avoid temperature fluctu-
ations
Take into account the environmental conditions. See "Technical Data".
Sufficient spacing for balances: > 15 cm all around the instrument
See also
Technical Data Page18
6 Pipette Calibration Module
4.2 Scope of delivery
4.2.1 MCP-R pipette calibration module
1
2
3
4
5
6
7
89
10
11
12
1Evaporation trap door 7Position pin, 2 pcs
2Cover 8Base plate
3Pipetting tanks, 12 pcs 9Centering gauge
4Holder for pipetting tanks 10 Height checking tool
5MCP-R casing 11 Tweezers
6Holder support 12 Test weighing pan
4.2.2 Documentation
Reference Manual
Production certificate
Declaration of Conformity
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7Pipette Calibration Module
4.3 Installing the MCP-R pipette calibration module on the balance
This instrument must be installed by a METTLER TOLEDO service technician.
5 Operation
5.1 Filling the evaporation trap
The evaporation trap includes two elongated recesses that should be filled with water. When the evaporation
trap is closed, the humidity inside increases until the air is saturated. This prevents evaporation of the liquid in
the pipetting tanks and ensures accurate weighing results.
The evaporation trap door is closed.
1 Press the button to remove the cover.
2 Fill both recesses, each with a maximum of 8 mL of
distilled water.
Note
In the event of an overflow, the water will drain outside
the instrument onto the underlying surface.
3 Place the cover and slightly press it down until it snaps
in.
4 Wait at least 120 minutes to allow the air in the evapo-
ration trap to reach saturation.
5.2 Performing a pipette calibration
For further information, consult the Reference Manual of the connected balance and the Operating
Instructions of the Calibry software.
www.mt.com/MCP-R-RM
According to ISO8655-6:2022, the readability of the balance should correspond to the nominal pipette volume
to be tested. The readability can be set in the tolerance profile of the method.
For more details about specific balance settings for pipette calibration, refer to the Reference Manual of the
balance.
The 12 pipetting tanks have a capacity of 17 mL each. They must be emptied regularly to avoid an overflow,
especially when calibrating pipettes with a larger volume (> 200 µL).
For performing a pipette calibration, a computer with the Calibry software installed is needed. The Calibry
software leads the user through the pipette calibration. The following steps explain the handling of the MCP-R
pipette calibration module while performing a pipette calibration.
8 Pipette Calibration Module
The evaporation trap is filled.
The evaporation trap door has been closed for at least 120 minutes, allowing the air in the evaporation trap
to reach saturation.
The balance is connected to a computer with the Calibry software installed.
An appropriate tolerance profile is selected.
1
2
3
1 Open the evaporation trap door (1).
2 Carefully pipette the required volume into the pipetting
tanks (2).
Note
In the event of an overflow, remove the excess liquid
immediately, see [Cleaning after an overflow
Page16].
3 Close the evaporation trap door (3).
4 Follow the instructions in the Calibry software.
5 Wait until all the pipetting tanks are weighed.
The weighing results are shown on the terminal
display.
6 Repeat the procedure until the Calibry software indicates
that the calibration process is finished.
Note
The results can be evaluated in the Calibry software.
5.3 Performing a test
For further information, consult the Reference Manual of the connected balance and the Operating
Instructions of the Calibry software.
5.3.1 Performance test or sensitivity test
The balance software leads the user through the test. The following steps explain the preparation of the MCP-R
pipette calibration module for the test.
Note
Performance test: METTLER TOLEDO recommends using OIML/ASTM test weights between 1g and 20g.
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9Pipette Calibration Module
Sensitivity test: METTLER TOLEDO recommends using an OIML/ASTM test weight of 100g.
An appropriate tolerance profile is selected.
1
2
3
4
1 Press the button to remove the cover.
2 Remove the pipetting tanks one by one with tweezers.
3 Vertically lift out the holder for pipetting tanks (1).
4 Place the test weighing pan (2) on the holder support
(3).
The instrument is ready for testing.
5 While performing the test, close the cover to avoid draft
(4).
5.3.2 Positioning test
For performing the positioning test, a computer with the Calibry software installed is needed. The Calibry
software leads the user through the test. The following steps show how to use the height checking tool.
Testing the pipetting position
1 Place the height checking tool (1) with the pipetting position side onto the border of the inner housing (2).
The upper end of the spring blades must be between the two tolerance lines (3). This applies to both
sides.
2 Check all 12 positions.
Pipetting position
min/max
Pipetting position
min/max
1
2
3
10 Pipette Calibration Module
Testing the weighing position
1 Place the height checker tool (1) with the weighing position side onto the border of the inner housing (2).
The upper end of the spring blades must be between the two tolerance lines (3). This applies to both
sides.
2 Check all 12 positions.
Weighing position
min/max
Weighing position
min/max
3 1
2
Failed test
If the test fails, see "Troubleshooting".
See also
Troubleshooting Page17
5.3.3 MCP repeatability test
For performing the test, a computer with the Calibry software installed is needed.
The pipetting tanks are empty.
All 12 pipetting tanks are correctly placed in the holder for pipetting tanks.
The balance is connected to a computer with the Calibry software installed.
Follow the instructions in the Calibry software.
Failed test
If the test fails, see "Troubleshooting".
See also
Troubleshooting Page17
6 Maintenance
To guarantee the functionality of the instrument and the accuracy of the weighing results, a number of
maintenance actions must be performed by the user.
The appropriate maintenance interval depends on your standard operating procedure (SOP).
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11Pipette Calibration Module
6.1 Maintenance tasks
Maintenance action Recommended interval Remarks
Cleaning Depending on the degree of pollution
In the event of an overflow
Depending on your internal regulations
(SOP)
see "Cleaning"
Emptying the containers Depending on the frequency of usage of the
instrument
Depending on your internal regulations
(SOP)
see "Emptying the containers"
Performing routine tests
(performance test,
positioning test, MCP
repeatability test, sensi-
tivity test).
After cleaning
After assembling the instrument
After a software update
Depending on your internal regulations
(SOP)
see "Performing a test"
see the Reference Manual of the
balance
See also
Cleaning Page15
Emptying the containers Page12
Performing a test Page9
6.2 Emptying the containers
The pipetting tanks and the evaporation trap can be emptied manually or with the help of a pump.
Note
The pump is not part of the delivery and can be purchased optionally, see [Accessories Page20].
6.2.1 Emptying the containers manually
6.2.1.1 Emptying the pipetting tanks
1 Remove the evaporation trap door.
2 Press the button to remove the cover.
3 Remove the pipetting tanks one by one with tweezers.
4 With tweezers, carefully pull out the glass tubes from the pipetting tanks.
5 Over a container suitable for liquid waste, turn the pipetting tanks upside down and drain out the water.
6 Dry the glass tubes and the pipetting tanks.
7 Insert the glass tubes into the pipetting tanks.
8 Insert the pipetting tanks into the holder for pipetting tanks.
The pipetting tanks are empty.
6.2.1.2 Emptying the evaporation trap
An absorbing sponge is usually sufficient to empty the evaporation trap.
1 Remove the evaporation trap door.
2 Press the button to remove the cover.
3 With a sponge, remove the liquid in the evaporation trap recesses.
The evaporation trap is empty.
12 Pipette Calibration Module
6.2.2 Emptying the containers with the pump
6.2.2.1 Assembling the pump
WARNING
Death or serious injury due to electric shock
Contact with parts that carry a live current can lead to death or injury.
1 Only use the METTLER TOLEDO power cable and AC/DC adapter designed for your
accessory.
2 Connect the power cable to a grounded power outlet.
3 Keep all electrical cables and connections away from liquids and moisture.
4 Check the cables and the power plug for damage and replace them if damaged.
NOTICE
Damage to the pump due to inappropriate handling
If the pump is switched on when it is not in use, it can get damaged.
Switch off the pump when it is not in use.
During normal usage, the pipetting tanks and the evaporation trap recesses contain water. The pump serves to
remove the water in a safe and efficient manner, without having to disassemble the instrument. The inlet tubing
has a metallic tube attached for easier handling. The outlet tubing serves to dispose of the aspirated liquid.
1
2
34
5
1 Install the cables in such a way that they cannot be
damaged or interfere with operation.
2 Insert the plug of the AC/DC adapter (1) into the power
socket.
3 Secure the plug by firmly tightening the knurled nut.
4 Insert the plug of the power cable into a grounded power
outlet that is easily accessible.
5 Connect the tubing with the metallic tube (2) to the
nozzle IN (3).
6 Connect the other tubing to the nozzle OUT (4).
7 Place the free end of the tubing into a container suitable for liquid waste (5).
6.2.2.2 Emptying the pipetting tanks
The pump is assembled.
The outlet tubing is placed in a container suitable for liquid waste.
1 Open the evaporation trap door.
2 Place the metallic tube inside one pipetting tank.
3 Switch on the pump.
The liquid is pumped out and collected in the container for liquid waste.
4 Switch off the pump.
5 Repeat this procedure for the other pipetting tanks.
The pipetting tanks are empty.
6.2.2.3 Emptying the evaporation trap
The pump is assembled.
The outlet tubing is placed in a container suitable for liquid waste.
1 Remove the evaporation trap door.
2 Press the button to remove the cover.
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13Pipette Calibration Module
3 Place the metallic tube into one elongated recess of the evaporation trap.
4 Switch on the pump.
The liquid is pumped out and collected in the container for liquid waste.
5 Switch off the pump.
6 Repeat this procedure for the other elongated recess of the evaporation trap.
The evaporation trap is empty.
6.3 Disassembling for cleaning
The containers are empty, see [Emptying the containers Page12].
The connected balance is disconnected from the power supply.
1
2
3
1 Remove the evaporation trap door (1).
2 Press the button (2) and remove the cover (3).
3 Press the button to remove the cover.
4
4 Remove the pipetting tanks one by one with tweezers
(4).
5
5 With tweezers, carefully pull out the glass tubes from the
pipetting tanks (5).
14 Pipette Calibration Module
6
6 Vertically lift out the holder for pipetting tanks (6).
7
7 Lift off the MCP-R casing from the balance (7).
8
8 Remove the holder support (8).
See also
Emptying the containers Page12
6.4 Cleaning
For further information on cleaning a balance, consult "8 Steps to a Clean Balance".
www.mt.com/lab-cleaning-guide
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15Pipette Calibration Module
NOTICE
Damage to the instrument due to inappropriate cleaning methods
If liquid enters the housing, it can damage the instrument. The surface of the instrument can be
damaged by certain cleaning agents, solvents, or abrasives.
1 Do not spray or pour liquid on the instrument.
2 Only use the cleaning agents specified in the Reference Manual (RM) of the instrument or the
guide "8 Steps to a Clean Balance".
3 Only use a lightly moistened, lint-free cloth or a tissue to clean the instrument.
4 Wipe off any spills immediately.
6.4.1 Cleaning the instrument
Cleaning around the instrument
Remove any dirt or dust around the instrument and avoid further contaminations.
Cleaning removable parts
Clean the removed part with a damp cloth or a tissue and a mild cleaning agent.
Cleaning not removable parts
1 Disconnect the connected balance from the AC/DC adapter.
2 Use a lint-free cloth moistened with a mild cleaning agent to clean the surface of the instrument.
3 Remove powder or dust with a disposable tissue first.
4 Remove sticky substances with a damp lint-free cloth and a mild solvent, e.g., isopropanol or ethanol
70%.
6.4.2 Cleaning after an overflow
In the event of an overflow, for example when overfilling the pipetting tanks, excess liquid must be removed
immediately.
1 If needed, empty the pipetting tanks, see Emptying the pipetting tanks.
2 Disassemble the remaining items.
3 Clean the items with a lint-free cloth or tissue, see [Disassembling for cleaning Page14].
4 Reassemble the instrument.
6.5 Putting into operation after cleaning
For further information, consult the Reference Manual of the connected balance.
www.mt.com/XPR-analytical-RM
1 Reassemble the instrument in reverse order.
2 Respect the warm-up time of the connected balance.
3 If needed, adjust the holder for pipetting tanks, see [Adjusting the holder for pipetting tanks Page17].
4 Perform a positioning test, see [Positioning test Page10].
5 Perform an MCP repeatability test, see [MCP repeatability test Page11].
The instrument is ready to be used.
16 Pipette Calibration Module
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