BD Alaris™ PK Plus 注射泵 MK4 取扱説明書

タイプ
取扱説明書
Alaris™ PK Plus
MK4
8005TIG03
zh
BDDF00647 1
1/56
Alaris™ PK Plus
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TCI ........................................................................................................ 4
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RS232 ............................................................ 48
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TCI ..................................................................................................51
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BDDF00647 1
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Alaris™ PK Plus
Alaris™ PK Plus MK4
w
MK4 MK4
3.4.x
Alaris PK Plus
4
1. /
2. (TIVA)
3. TCI (TIVA)
4. TCI
(TCI)
(TCI)
Alaris PK Plus
/
Alaris PK Plus
Alaris PK Plus
Alaris PK Plus Alaris PK Plus
(DFU)
TCI
/
BD - - TCI
- Alaris PK Plus
TCI
(ASTRA-ZENECA) TCI Marsh
TCI Minto Gepts
w
BD
BDDF00647 1
3/56
Alaris™ PK Plus
Alaris PK Plus
Alaris PK Plus
Alaris PK Plus
1.0 / 5.0 /
w
BD bd.com
BD
Battery Indicator
PURGEON/OFF/
w
BDDF00647 1
4/56
Alaris™ PK Plus
TCI
TCI
-
1/
1
Kruger-Thiemer
2
Schwilden
3
80 90 TCI
(V1) (V2)
(V3)k
12
k
21
k
31
k
13
k
10
2
TCI
TCI
TCI
cl2
k
12
k
21
k
31
k
10
k
13
cl1
V2 V1 V3
cl3
2
4
90
TCI
Cp50 Cp95 50% 95% Ausems
5
90
6 7 8
3 k
1e
k
eo
BDDF00647 1
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Alaris™ PK Plus
TCI
k
eo
TCI
3
cl2
k
12
k
21
k
31
k
10
k
eo
k
13
cl1
V2 V1 V3
cl3
3-
TCI Alaris PK
Plus
TCI
TCI /
1. Danhof M: Does variability explain (all) variability in drug effects ?, Topics in pharmaceutical science.Edited by Breimer DD, Crommelin DJA, Midha KK.Noordwijk, Amsterdam
Med.Press BV, 1989, pp 573-586
2. Kruger-Theimer E: Continuous intravenous infusion and multicompartment accumulation.Eur J Pharmacol 1968; 4: 317-324
3. Schwilden H: A general method for calculating the dosage scheme in linear pharmacokinetics.Eur J Clin Pharmacol 1981; 20: 379-86
4. Shafer SL: Towards optimal intravenous dosing strategies.Seminars in Anesthesia 1993; 12: 222-234
5. Ausems ME, Hug CC, Jr., Stanski DR, Burm AG: Plasma concentrations of alfentanil required to supplement nitrous oxide anesthesia for general surgery.Anesthesiology 1986;
65: 362-73
6. Schnider TW, Minto CF, Stanski DR: The effect compartment concept in pharmacodynamic modelling.Anaesthetic Pharmacology Review 1994; 2: 204-213
7. Shafer SL: Principles of pharmacokinetics and pharmacodynamics., Principles and practice of anesthesiology.2nd Edition.Edited by Longnecker DE, Tinker JH, Morgan GE.New
York, Mosby-Year Book, 1998, pp 1159- 1210
8. Shafer SL, Gregg KM: Algorithms to rapidly achieve and maintain stable drug concentrations at the site of drug effect with a computer-controlled infusion pump.J
Pharmacokinet Biopharm 1992; 20: 147-69
TCI
Alaris PK Plus /
/
TCI
BDDF00647 1
6/56
Alaris™ PK Plus
TCI
Alaris PK Plus
Marsh
16
/
15 /
Vc = 0.228 x x
-1
)
k
10
= 0.119
-1
k
12
= 0.112
-1
k
13
= 0.0419
-1
k
21
= 0.055
-1
k
31
= 0.0033
-1
k
eo
= 0.26
-1
Marsh et al.: Brit J Anaesth 1991, 67, 41-48
Minto
12
/
20 /
Vc = 5.1 - 0.0201 x - 40+ 0.072 x (lbm - 55)
V2 = 9.82 - 0.0811 x - 40+ 0.108 x (lbm - 55)
V3 = 5.42
cl1 = 2.6 - 0.0162 x - 40+ 0.0191 x (lbm - 55)
cl2 = 2.05 - 0.0301 x - 40
cl3 = 0.076 - 0.00113 x - 40
k
10
= cl1 / Vc
k
12
= cl2 / Vc
k
13
= cl3 / Vc
k
21
= cl2 / V2
k
31
= cl3 / V3
k
eo
= 0.595 - 0.007 x - 40
Minto et al.: Anesthesiology 1997, 86, 10 - 33
Gepts
12
/
2 /
Vc = 14.3 l
k
10
= 0.0645
-1
k
12
= 0.1086
-1
k
13
= 0.0229
-1
k
21
= 0.0245
-1
k
31
= 0.0013
-1
Gepts et al.: Anesthesiology 1995, 83, 1194-1204
5.6 k
eo
k
eo
= 0.17559
-1
Shafer et al Anesthesiology.1991 Jan;74(1):53-63
BDDF00647 1
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Alaris™ PK Plus
Alaris PK Plus
Alaris PK Editor (1000CH00016)
1. Alaris PK Editor
* TIVA TCI
PK/PD
Alaris PK
2. Alaris PK Editor
*
**
3. ALaris PK Editor
4. Alaris PK Plus Alaris PK Editor Transfer Tool
5.
Alaris PK Plus CRC
Alaris PK Verification Tool
CRC
CRC CRC
6.
w
**
BDDF00647 1
8/56
Alaris™ PK Plus
/
/
RS232 (PE)
(
M
D
I
)
BDDF00647 1
9/56
Alaris™ PK Plus
a
/ - 3
b
- LED
h
- LED
R
- 2
Alaris PK Editor
60
i
/ -
(VI)
-
VI
d
-
e
-
f
- /
g
-
j
-
30
S
-
BDDF00647 1
10/56
Alaris™ PK Plus
x
(PE)
y
RS232/
l
CF
IP32
15° 2.5mm
1000SP01294 IP33
r
2007/47/EC 93/42/EEC
T
t
U
W
+40°C
0°C
- 0 40
BDDF00647 1
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Alaris™ PK Plus
TIVA
TCI
CONFIRM TIME
TCI -
MORE
MORE
BMI 21.6
BACK TCI 20 TCI
BDDF00647 1
12/56
Alaris™ PK Plus
l
-
N
-
Alaris Editor
C
D
E
F
-
-
-
BDDF00647 1
13/56
Alaris™ PK Plus
m
3
n
o
/
I
EN 1789
IV
J
BDDF00647 1
14/56
Alaris™ PK Plus
A
V
RS232/ RS232/
(ESD)
L
BD
Alaris BD Alaris
BD Alaris
Alaris Alaris
BD
BDDF00647 1
15/56
Alaris™ PK Plus
M
BD
MR
(MRI) MRI MRI
MRI BD
MRI
(EMI)
(TSM)
BD
EMC BD
CISPR 111 A
IEC/EN60601-1-2 IEC/EN60601-2-24
K
15 10 /
BDDF00647 1
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Alaris™ PK Plus
w
1.
2.
Alaris PK Plus
CD
3. 2.5 S
1. Select Language
2.
f
3. OK
w
BDDF00647 1
17/56
Alaris™ PK Plus
w
15 40 mm
I.V.
*
*
1.
2.
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1. /*
2.
3.
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*Alaris DS Alaris
BDDF00647 1
18/56
Alaris™ PK Plus
9 10
PURGE SYRINGE PURGE
w
< 0.5 /
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w
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BDDF00647 1
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Alaris™ PK Plus
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1.
2.
3.
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BD Alaris™ PK Plus 注射泵 MK4 取扱説明書

タイプ
取扱説明書